STAT3 Antibody

h1 class=titleSTAT3 Antibody/h1
div id=node-1736 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong251107/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Data and Images/h4
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pspan class=inline lefta href=http://www.abbiotec.com/image/stat3-staining-human-breast-cancerimg class=image image-medium title=STAT3 staining in human breast cancer: STAT3 staining in human breast cancer tissue: Paraffin-embedded human breast cancer tissue is stained with STAT3 Antibody (Cat. No. 251107) used at a 1:200 dilution. alt=STAT3 staining in human breast cancer: STAT3 staining in human breast cancer tissue: Paraffin-embedded human breast cancer tissue is stained with STAT3 Antibody (Cat. No. 251107) used at a 1:200 dilution. width=248 height=254 src=http://www.abbiotec.com/files/images/251107_breast.jpg //aspan style=width: 246px class=captionstrongSTAT3 staining in human breast cancer: /strongSTAT3 staining in human breast cancer tissue: Paraffin-embedded human breast cancer tissue is stained with STAT3 Antibody (Cat. No. 251107) used at a 1:200 dilution./span/span/p
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h4Description/h4
pThe signal transducer and activator of transduction 3 (STAT3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome)./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pSignal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P40763P40763/abr /
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h4Clonality/h4
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT3./p
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h4Application Notes/h4
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pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:100-1:500/p
pstrongReacts with/strongnbsp; :H | M | R | Other/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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