SSA Antibody

The 60 kDa SS-A/Ro ribonucleoprotein (SSA) is an RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. SSA may protect these RNAs from degradation. SSA is phosphorylated by ATM or ATR upon DNA damage. Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with normal cellular SSA2.