Sotalol
- 貨號 Cat. No.
- S2509
- 規格 Size
- 5~200mg
- 品牌 Brand
- Selleckchem
Description
Sotalol
Catalog No.S2509
Sotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM
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Biological Activity
Sotalol (Betapace) is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 µM. Sotalol definitely distinctly located binding site to interfere with K+ permeation; both enantiomers associated with a rate close to 5 ËŸ 105 /mol/ sec with the open pore thereby flicker-blocking cardiac K(ATP) channels. [1][2]
Chemical Information
| Molecular Weight (MW) | 308.82 |
|---|---|
| Formula | C12H20N2O3S.HCl |
| CAS No. | 959-24-0 |
| Storage | 3 years -20℃Powder |
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| 6 months-80℃in DMSO | |
| Syonnyms | Sotalex |
| Solubility (25°C) * | In vitro | DMSO | 62 mg/mL (200 mM) |
|---|---|---|---|
| Water | 62 mg/mL (200 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
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| Mass(mg) | 0.30882 | 3.0882 | 6.1764 | 9.2646 |