Sodium butyrate
- 貨號 Cat. No.
- 1609-1000
- 規格 Size
- 1 g
Description
MOLECULAR FORMULA: C4H7O2 . Na
MOLECULAR WEIGHT: 110.1
CAS NUMBER: 156-54-7
PURITY: >99% by HPLC
APPEARANCE: White solid
SOLUBILITY: Soluble in water
STORAGE CONDITIONS: -20oC
DESCRIPTION:
A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.
CAUTION: May be harmful by inhalation, in contact with skin or if swallowed.
USAGE: For research use only. Not to be used in humans.