SOD-1 Antibody

Antibody Target: SOD-1

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen: Synthetic peptide surrounding amino acid 131 of human SOD

Accession#: AAR21563

Gene ID: 6647

Appearance: Colorless liquid

Concentration: 0.2 mg/ml

Formulation: 100 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Species Reactivity: hu/ms/rt

Application: WB/IP/IHC

Application & Usage: Western blotting (0.5-4 µg/ml), immunoprecipitation (20 µg/ml) and immunohistochemistry (20 µg/ml, frozen & paraffin). However, the optimal concentrations should be determined individually.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: SOD (Superoxide Dismutase) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide, and it also catalyzes prooxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases.