SMAD3 (5G11) Antibody

SMAD3 (Mothers against decapentaplegic homolog 3) is a tumor suppressor protein. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD3 is a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.