Smad2/3 Antibody
Antibodies
- 貨號 Cat. No.
- 251894
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC
- Reactivity
- Human 、 Mouse
Description
SMAD family member 2 (SMAD2/3) is receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. SMAD2/3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. SMAD2/3 acts as a tumor suppressor in colorectal carcinoma.
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