Silodosin

貨號 Cat. No.: S1613
規格 Size: 10mM/1mL~10mg
品牌 Brand: Selleckchem

Description

Silodosin

Catalog No.S1613

Silodosin is an α1-adrenoceptor antagonist with high uroselectivity.

Size

Price

Stock

Quantity

10mM/1mLIn DMSO	USD 428	In stock	0 1 2 3 4 5 6 7 8 9 10
5mg	USD 214	In stock	0 1 2 3 4 5 6 7 8 9 10
10mg	USD 403	In stock	0 1 2 3 4 5 6 7 8 9 10

Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw

Biological Activity

Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. It causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it causes practically no orthostatic hypotension (in contrast to other α1 blockers). On the other hand, the high selectivity seems to cause more problems with ejaculation. [1]

Clinical Trial Information( data from http://clinicaltrials.gov)

NCT Number	Recruitment	Conditions	Sponsor /Collaborators	Phases
NCT02090439	Active, not recruiting	Kidney Stone\|Expulsive Medical Therapy	Centre Hospitalier Departemental Vendee	Phase 3
NCT02106182	Recruiting	Nocturia\|Benign Prostatic Hyperplasia	JW Pharmaceutical	Phase 4
NCT01560091	Not yet recruiting	Kidney Stones	Albert Einstein Healthcare Network
NCT01533389	Completed	Ureteral Stone	JW Pharmaceutical	Phase 4
NCT01757769	Completed	Benign Prostatic Hyperplasia	Recordati Industria Chimica e Farmaceutica S.p.A.	Phase 4

Chemical Information

Download Silodosin SDF

Molecular Weight (MW)	495.53
Formula	C25H32F3N3O4
CAS No.	160970-54-7

Storage	3 years -20â„ƒPowder
Storage	6 months-80â„ƒin DMSO
Syonnyms	KAD 3213, KMD 3213

Solubility (25°C) *	In vitro	DMSO	99 mg/mL (199 mM)
		Water	<1 mg/mL (<1 mM)
		Ethanol	99 mg/mL (199 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.