Sheep antibody to rh Basic FGF: Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Heparin-binding growth factor 2; HBGF-2; Basic fibroblast growth factor; bFGF; Prostatropin; FGF2; FGFB

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

IHC. A concentration of 1 µg/mL is recommended for immunohistochemistry. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=60

 

Description (Long Description) : 

Fibroblast growth factors (FGFs) bind heparin and exhibit widespread mitogenic and neurotrophic activities in a variety of different cells including mesenchymal, neuroectodermal and endothelial cells. There are differences in the tissue distribution and concentration of these 2 growth factors. aFGF (FGF-1) and bFGF (FGF-2) are present in relatively high levels in CNS. aFGF is expressed by a subset of neuronal populations, while bFGF is expressed by astrocytes, both lack signal peptides. Human bFGF is a 17.2 kDa protein containing 155 amino acid residues. FGF-2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. SUBUNIT: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2. MISCELLANEOUS: This protein binds heparin more strongly than does aFGF. SIMILARITY: Belongs to the heparin-binding growth factors family.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized

 

Immunogen (Antigen) :Recombinant human basic FGF

 

Kit_Components :

 

MSDS (File name) :