SHBG

Sex-Hormone-Binding Globulin is a blood transport
protein for steroids hormones with an high affinity
for testosterone and estradiol.
The SHBG levels are higher in women than in men
and increase during pregnancy and in women taking
oral contraceptives. Low levels are found in cases of
hirsutism, hyperandrogenism and may be
encountered in individuals with Cushing’s or
polycystic ovarian syndrome.
High serum level for men are associated with
hypogonadism, hepatic cirrhosis and thyrotoxicosis.