sFRP-1 Antibody
Antibodies
- 貨號 Cat. No.
- 251666
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC
- Reactivity
- Human 、 Mouse
Description
Secreted frizzled-related protein 1 (sFRP-1) functions as a modulator of Wnt signaling through direct interaction with Wnts. sFRP-1 has a role in regulating cell growth and differentiation in specific cell types. sFRP-1 decreases intracellular beta-catenin levels. sFRP-1 is down-regulated in colorectal and breast tumors, and up-regulated in uterine leiomyomas under high estrogenic conditions.
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