Senescence Detection Kit (Fluorometric)

Kits

貨號 Cat. No.
K991-100
規格 Size
K991-100
Reactivity
Mammalian
Sample Type
Adherent/Suspension Cells

Description




Alternate Name :


 

Tag Line :


Simple, sensitive, one-step assay to measure senescence cells using FACS


 

Storage Conditions: -20°C


 

Shelf life: 12 months


 

Summary :


• Detection method- FACS (FL1 channel)
• Application-Detection of senescence cells -Screening potential senescence inducers/inhibitors


 

Detection Method: FACS (FL1 channel)


 

Features & Benefits:


Simple, one step protocol


 

Description:


Senescence is thought to be a tumor suppressive mechanism and an underlying cause of aging. Senescence represents an arrested state in which the cells remain viable, but not stimulated to divide by serum or passage in culture. Senescent cells display increase of cell size, senescence-associated expression of β-galactosidase (SA-β-Gal) activity, and altered patterns of gene expression. The Senescence detection kit is designed to fluorescently detect SA-β-Gal activity in cultured cells by FACS. The SA-β-Gal is present only in senescent cells and is not found in pre-senescent, quiescent or immortal cells


 





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