Semagacestat
Chemical Compounds
- 貨號 Cat. No.
- M2277
- 規格 Size
- 10mg,50mg
- 品牌 Brand
- No Brand
Description
Semagacestat (LY450139) is a γ-secretase blocker with an IC50 of 15 nM. Semagacestat also inhibits Notch signaling with IC50 of 14.1 nM. Semagacestat blocks the enzyme γ-secretase, which (along with β-secretase) is responsible for APP proteolysis.
