SCD Antibody

Antibody Target :SCD

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen Sequence: Synthetic peptide surrounding amino acid 206 of rat SCD

Accession#: NP_114029

Gene ID: 83792

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-SCD polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Species Reactivity: hu/ms/rt/pg/hst

Application: WB

Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody recognizes a ~37 kDa SCD. Rat kidney tissue lysate can be used as a positive control.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme involved in the synthesis of oleate and palmitoleate. Oleate and palmitoleate are the main components of membrane phospholipid, triglycerides and cholesterol esters. SCD plays an important role in cellular cholesterol homeostasis and also in the secretion processes of triacylglycerol and phospholipid. Inhibition of SCD could be a useful treatment for metabollic disorders such as obesity and hepatic steatosis.