Saxagliptin
Chemical Compounds
- 貨號 Cat. No.
- M3435
- 規格 Size
- 10mg,25mg,100mg
- 品牌 Brand
- No Brand
Description
Saxagliptin (Onglyza) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM. BI 1356 inhibited DPP-4 activity in vitro with an IC (50) of approximately 1 nM, compared with sitagliptin (19 nM), alogliptin (24 nM), saxagliptin (50 nM), and vildagliptin (62 nM). BI 1356 was a competitive inhibitor, with a K (i) of 1 nM.
