Saracatinib
Chemical Compounds
- 貨號 Cat. No.
- M1659
- 規格 Size
- 10mg,50mg,100mg,200mg
- 品牌 Brand
- No Brand
Description
Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.Saracatinib (AZD0530) demonstrated potent antimigratory and antiinvasive effects in vitro, and inhibited metastasis in a murine model of bladder cancer. Antiproliferative activity of AZD0530 in vitro varied between cell lines (IC50=0.2 ~10 mM).
