S1RA
Chemical Compounds
- 貨號 Cat. No.
- M2596
- 品牌 Brand
- No Brand
Description
S1RA is a potent and selective sigma-1 receptor (σ1R, Ki=17 nM), which showes good selectivity against σ2R (Ki > 1000 nM). S1RA dose-dependently inhibites Formalin-induced nociception (both phases), capsaicin-induced mechanical hypersensitivity and sciatic nerve injury-induced mechanical and thermal hypersensitivity.
