Renin Activity LIA

pRenin Activity LIA/p
pimg alt=For Research Use Only src=http://www.alpco.com/img/ruo.gif align=absMiddle / For Research Use Only/p
div class=prod_head_infohr /
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div class=prod_specSample Type:/div
div class=prod_spec_infoEDTA plasma/div
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div class=prod_specbSample Size:/b/div
div class=prod_spec_info200 micro;l/div
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div class=prod_specbSize:/b/div
div class=prod_spec_info96 wells/div
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div class=prod_spec_box
div class=prod_specbRange:/b/div
div class=prod_spec_info0.4 - 50 ng/ml/div
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div class=prod_specbSensitivity:/b/div
div class=prod_spec_info0.9 ng/ml/div
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div class=prod_specbIncubation Time:/b/div
div class=prod_spec_info1 Hour 15 Min/div
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pbSummary:/b/p
Renin-Angiotensin-Aldosterone System (RAAS) is a major long-term regulator of blood pressure, blood volume, and electrolyte (Na+ and K+) balance. Each nephron releases renin when it receives various stimuli, either as a fall in artery pressure or a decrease in distal tubular sodium supply. Renin liberates angiotensin-I from angiotensinogen. Angiotensin-I is transformed to angiotensin-II largely in pulmonary circulation by angiotensin converting enzyme (ACE). Angiotensin-II raises blood pressure by direct arteriolar vasoconstriction, promoting sodium retention, and stimulating the secretion of aldosterone by the adrenal cortex. Aldosterone also exerts effects to restore sodium balance and lift arterial pressure. Determination of circulating renin, Ang-II, and aldosterone, can aid in the study of Primary Aldosteronism and other forms of hypertension./div
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