Relaxin, ELISA

貨號 Cat. No.
K 9210
規格 Size
96 Tests
品牌 Brand
IDS

Description

































Article number: K 9210
Method: ELISA
Tests: 96 Tests
Matrix: Serum, Urine, Cell Culture Supernatant, Tissue Plasma, Seminal Plasma
Volume: 100 µl
Incubation time: 16h; 2h; 1h; 15min
Standards: 4-125 pg/ml







Relaxin belongs to the insulin family and was originally described as a hormone produced in the ovaries, which was mainly detectable during pregnancy and birth. However, latest investigations have shown, that synthesis of relaxin could also occur in the placenta, endometrium, mammary glands, or prostata. The binding of relaxin to specific receptors has been observed in the brain, uterus and the heart, which speaks in favour for the multi-functionality of this hormone. In the first animal models (rat) relaxin functions as a strong chronotropic and inotropic agent in normotensive as well as in spontane hypertensive rats. The mechanisms, which lead to the increase in heart frequency and promote contractions of the heart muscles, are still unclear. The effects were however stronger in comparison to angiotensin II and it is assumed that this effect is mediated via specific receptors in the heart.



 

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