Regorafenib
Chemical Compounds
- 貨號 Cat. No.
- M1669
- 規格 Size
- 10mg,50mg,100mg
- 品牌 Brand
- No Brand
Description
Regorafenib (BAY 73-4506) is a novel oral multikinase inhibitor of c-KIT, VEGFR2, B-Raf with IC50s of 17, 40 and 69 nM respectively. Regorafenib (BAY 73-4506) administered once orally at 10 mg/kg significantly decreased the extravasation of Gadomer in the vasculature of rat GS9L glioblastoma tumor xenografts.
