Antibodies
Racecadotril
- 貨號 Cat. No.
- S2503
- 規格 Size
- 10mM/1mLã€50mg
- 品牌 Brand
- Selleckchem
Description
Racecadotril
Catalog No.S2503
Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM
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Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 µM.Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy. [1][2]
Chemical Information
| Molecular Weight (MW) | 385.48 |
|---|---|
| Formula | C21H23NO4S |
| CAS No. | 81110-73-8 |
| Storage | 3 years -20℃Powder |
|---|---|
| 6 months-80℃in DMSO | |
| Syonnyms | Acetorphan |
| Solubility (25°C) * | In vitro | DMSO | 22 mg/mL (57 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 77 mg/mL (199 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
|---|---|---|---|---|
| Mass(mg) | 0.38548 | 3.8548 | 7.7096 | 11.5644 |
