Rabbit polyclonal antibody to Neuropathy target esterase (1323-1348): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Neurotoxic esterase; NTE; NTEMND; Patatin like phospholipase domain containing 6; PNPLA6; SPG39; swisscheese; sws;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Zebra fish NTE has a predicted length of 1,348 residues and MW of 150 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Enzymatic antigen retrieval is required. Also the recommended concentration for formalin/acetone fixed frozen tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

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(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=631

 

Description (Long Description) : 

Neuropathy target esterase (NTE), also known as Patatin like phospholipase domain containing 6, is a neuronal membrane protein and a target protein for neuropathic organophosphorus (OP) compounds. The functions of NTE are not yet fully understood. NTE is suggested to have a role in neuronal development. Gene mutations in NTE have been linked with neurodegenerative diseases such motor neuron disease (MND) and amyotrophic lateral sclerosis (ALS).

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (DEDKTVRQRKNVSRDPNADFSGVSDC) corresponding to a region (1323-1348) from the C-terminus of zebrafish Neuropathy target esterase. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

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