Rabbit polyclonal antibody to human Tyrosine-protein phosphatase non-receptor type 11 (578-592): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

EC 3.1.3.48; Protein-tyrosine phosphatase 2C; PTP-2C; PTP-1D; SH-PTP3; SH-PTP2; SHP-2; Shp2; PTPN11; PTP2C; SHPTP2;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human SHP2 has a predicted length of 597 residues and MW of 68 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=575

 

Description (Long Description) : 

Tyrosine-protein phosphatase non-receptor type 11 (SHP2) plays a regulatory role in various cell signaling events such as mitogenic activation, metabolic control, transcription regulation and cell migration. SHP2 is highly expressed in the cytoplasm of heart, brain and skeletal muscle tissue. At least 3 isoforms of SHP2 are produced by alternative splicing.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (EDSARVYENVGLMQQ) corresponding to a region (578-592) from the C-terminus of human Tyrosine-protein phosphatase non-receptor type 11. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :