Rabbit polyclonal antibody to human STAT3 (686-698): Affinity purified

ZZZZ_Status (Active, Disc) : Discontinued

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human STAT3 (isoform 1) has a predicted length of 770 residues and MW of 88 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=569

 

Description (Long Description) : 

STAT3 belongs to the STAT (signal transducers and activators of transcription) family of proteins. STAT proteins undergo tyrosine/serine phosphorylation in response to cytokines and growth factors. Phosphorylated STAT3 forms a homodimer or heterodimer with related family members such as STAT1. Phosphorylated STAT proteins are translocated to the nucleus where they act as transcription factors. STAT3 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas tissues.  Alternative splicing of the STAT3 gene gives rise to at least 2 isoforms.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (YCRPESQEHPEAD) corresponding to a region (686-698) from human STAT3. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :