Rabbit polyclonal antibody to human STAT1 alpha (718-733): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Transcription factor ISGF-3 components p91/p84; STAT1; p91;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human STAT1 (isoform alpha/p91) has a predicted length of 750 residues and MW of 87 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=568

 

Description (Long Description) : 

STAT1 belongs to the STAT (signal transducers and activators of transcription) family of proteins. STAT proteins undergo tyrosine/serine phosphorylation in response to cytokines and growth factors. As a result of this phosphorylation, STAT proteins  form dimers and are translocated to the nucleus where they act as transcription factors. Alternative splicing of the STAT1 gene gives rise to the STAT1 alpha and beta isoforms.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Liquid (0.5mL). 50% glycerol, 0.9mg NaCl and 0.2mg Na2HPO4

 

Immunogen (Antigen) :A synthetic peptide (QTTDNLLPMSPEEFDE) corresponding to a region (718-733) from the C-terminus of human STAT1 isoform alpha/p91. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

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