Rabbit polyclonal antibody to human Runt-related transcription factor 2 (244-258): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Core-binding factor subunit alpha-1; CBF-alpha-1; Acute myeloid leukemia 3 protein; Oncogene AmL-3; Polyomavirus enhancer-binding protein 2 alpha A subunit; PEBP2-alpha A; PEA2-alpha A; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core-binding factor alpha A subunit; Osteoblast-specific transcription factor 2; OSF-2; RUNX2; AmL3; CBFA1; OSF2; PEBP2A;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Western Blotting (WB). A concentration of 0.1-0.5µg/mL is recommended for WB. Human RUNX2 (isoform 1) has a predicted length of 521 residues and MW of 57 kDa.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=607

 

Description (Long Description) : 

Runt-related transcription factor 2 (RUNX2) is a member of the RUNX family of transcription factors. RUNX2 has an Runt domain and can bind DNA both as a monomer or as a subunit of a heterodimeric complex. RUNX2 has a role in osteoblastic differentiation and skeletal morphogenesis and is essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. RUNX2 is specifically expressed in the nucleus of osteoblasts. At least 3 isoforms are produced by alternative splicing.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide corresponding to a region (244-258 aa) from human Runt-related transcription factor 2. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :