Rabbit polyclonal antibody to human phosphomevalonate kinase (135-151): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Phosphomevalonate kinase; PMKase; EC 2.7.4.2; PMVK; PMKI;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human phosphomevalonate kinase has a predicted length of 192 residues and MW of 22 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=543

 

Description (Long Description) : 

The enzyme phosphomevalonate kinase (PMVK) catalyzes the conversion of 5-phosphomevalonate into 5-diphosphomevalonate in the cholesterol biosynthetic pathway. PMVK is found in the peroxisome of heart, liver, skeletal muscle, kidney and pancreas tissue with lower levels in brain, placenta and lung.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (EQSRQQRGWVFTPGVDD) corresponding to a region (135-151) from human phosphomevalonate kinase (PMVK). To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

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MSDS (File name) :