Rabbit polyclonal antibody to human Matrix metalloproteinase-16 (582-598): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

MMP-16; EC 3.4.24.; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP; MMP-X2; MMP16; MMPX2;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human MMP16 (isoform Long) has a predicted length of 607 residues and MW of 70 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues as well as formalin or acetone fixed frozen tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=563

 

Description (Long Description) : 

The matrix metalloproteinases (MMPs) are a large family of  zinc endopeptidases. All MMPs are synthesized as inactive proenzymes. The activation of these proenzymes is a critical step that leads to degradation of extracellular matrix components such as fibronectin and collagen type III. At least 2 isoforms of MMP16 are produced by alternate splicing. The Long isoform is a single-pass type 1 membrane protein. The Short isoform is secreted. Both forms of MMP16 activate MMP2 (progelatinase A) by cleavage.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (YTVFQFKRKGTPRHILY) corresponding to a region (582-598) from human Matrix metalloproteinase-16. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :