Rabbit polyclonal antibody to human Lamin B1 (570-586): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

LMNB1; LMN2; LMNB;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human Lamin B1 (precursor) has a predicted length of 586 residues and MW of 66 kDa. A concentration of 1.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. A concentration of 1.0 µg/mL is also recommended for formalin/acetone fixed tissues. Antigen retrieval by Pepsin and Trypsin is required in acetone fixed cells. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=626

 

Description (Long Description) : 

Lamins belong to the intermediate filament family of proteins. They are structural components of the nuclear lamina and are thought to be involved in nuclear stability, chromatin structure and gene expression. There are two main types of lamins; A and B. The A type lamins include A, C and Adel10. The B-type lamins, B1 and B2, arise from two distinct genes.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (FHQQGTPRASNRSCAIM) corresponding to amino acids 570-586 from human Lamin B1. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :