Rabbit polyclonal antibody to human Lamin A + C (451-468): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 2.0 µg/mL is recommended for WB. Human Lamin A has a predicted length of 664 residues and MW of 74 kDa. Human Lamin C has a predicted length of 572 residues and MW of 65 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=540

 

Description (Long Description) : 

Lamins belong to the intermediate filament family of proteins. They are structural components of the nuclear lamina and are thought to be involved in nuclear stability, chromatin structure and gene expression. There are two main types of lamins; A and B. Alternative splicing of the Type A lamin gene produces at least 2 isoforms; Lamin A and Lamin C.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (FVRLRNKSNEDQSMGNWQ) corresponding to amino acids 451-468 from human Lamin A and Lamin C. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :