Rabbit polyclonal antibody to human Histamine H3 receptor (428-445): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

HH3R; G-protein coupled receptor 97; HRH3; GPCR97;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Western Blotting (WB). A concentration of 0.75 µg/mL is recommended for WB. Human Histamine H3 receptor (isoform 1) has a predicted length of 445 residues and MW of 49 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=585

 

Description (Long Description) : 

The Histamine H3 receptor is a multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. This protein is primarily expressed in the CNS. At least 7 isoforms are produced by alternative splicing. Expression of these isoforms varies with isoform 3 and isoform 7 being highly expressed in the thalamus, caudate nucleus and cerebellum while isoforms 5 and  6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (CPQKLKIQPHSSLEHCWK) corresponding to a region (428-445) from the C-terminus of human Histamine H3 receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :