Rabbit polyclonal antibody to human Heparanase (161-171): Affinity purified

ZZZZ_Status (Active, Disc) : Discontinued

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Heparanase-1; Hpa1; Endo-glucoronidase; HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human Heparanase (precursor) has a predicted length of 543 residues and MW of 62 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=606

 

Description (Long Description) : 

Heparanase cleaves heparan sulfate proteoglycans into heparan sulfate side chains and core proteoglycans. The 65 kDa proheparanase precursor is proteolytically processed into a linker peptide of 8 kDa and a 50 kDa product harboring the active site. The active form of Heparanase is a heterodimer of these two subunits. Heparanase is highly expressed in placenta and spleen and weakly expressed in lymph node, thymus, peripheral blood leukocytes, bone marrow, endothelial cells, fetal liver and tumor tissues.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (KNSTYSRSSVD) corresponding to a region (161-171) from human Heparanase. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :