Rabbit polyclonal antibody to human Growth Hormone receptor (101-117): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

GHR; GH receptor; Somatotropin receptor;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.75 µg/mL is recommended for WB. Human Growth Hormone receptor (isoform GHRfl) has a predicted length of 638 residues and MW of 72 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

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Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=588

 

Description (Long Description) : 

Growth Hormone receptor (GRH) is a single-pass type I membrane protein and a receptor for pituitary gland growth hormone. The binding of growth hormone to the receptor leads to the dimerization of the receptor and the activation of signal transduction pathways leading to growth. At least 4 isoforms are produced by alternative splicing.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (CPDYVSAGENSCYFNSS) corresponding to a region (101-117) from human Growth Hormone receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

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