Rabbit polyclonal antibody to human Growth-associated protein 43 (216-238): Affinity purified

ZZZZ_Status (Active, Disc) : Discontinued

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Neuromodulin; GAP43; PP46; p57; B-50; F1; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5µg/mL is recommended for WB. Human GAP-43 has a predicted length of 238 residues and MW of 25 kDa. A concentration of 0.5-1µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is recommended.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=527

 

Description (Long Description) : 

Growth-associated protein 43 (GAP-43) is expressed by developing and regenerating neurons, and to a lesser extent, reactive glial cells.  It is also a major component of neuronal growth cones. GAP-43 binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence. Phosphorylation of GAP-43 by a protein Kinase C is correlated with certain forms of synaptic plasticity. GAP-43 is used to specifically label injured neurons and to score neuronal regeneration.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 added as preservative

 

Immunogen (Antigen) :A synthetic peptide corresponding to a region (216-238) from human Growth-associated protein 43 (GAP-43). To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :