Rabbit polyclonal antibody to human Glial Fibrillary Acidic Protein (341-356): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Astrocyte; Glial fibrillary acidic protein; GFAP;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human GFAP has a predicted length of 432 residues and MW of 50 kDa. A concentration of 2.0 µg/mL is recommended to detect GFAP in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

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(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=618

 

Description (Long Description) : 

Glial Fibrillary Acidic Protein (GFAP) is a 50 kDa intra-cytoplasmic filamentous protein of the cytoskeleton in astrocytes. During the development of the central nervous system, it is a cell-specific marker that distinguishes astrocytes from other glial cells. GFAP immunoreactivity has been shown in immature oligodendrocytes, epiglottic cartilage, pituicytes, papillary meningiomas, myoepithelial cells of the breast and in non-CNS: Schwann cells, salivary gland neoplasms, enteric glia cells, and metastasizing renal carcinomas. At least 3 isoforms are produced from alternate splicing. These isoforms differ in the C-terminal region which is encoded by alternative exons.

 

Expiry_Date : 

12 months after purchase.

 

Format (Form) : 

Lyophilized from 1.2% sodium acetate, 2mg BSA, 0.2mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (EMARHLQEYQDLLNVK) corresponding to a region (341-356) from human Glial Fibrillary Acidic Protein. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

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