Rabbit polyclonal antibody to human Cyclooxygenase-2 (28-50): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Prostaglandin G/H synthase 2; EC 1.14.99.1; Cyclooxygenase-2; COX-2; Prostaglandin-endoperoxide synthase 2; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; PHS II; PTGS2; COX2;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human COX-2 (precursor) has a predicted length of 604 residues and MW of 69 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat activated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=590

 

Description (Long Description) : 

Cyclooxygenase (COX) is an important enzyme in the conversion of arachidonic acid to Prostaglandin H2, the precursor of the series-2 prostanoids. At least 3 splice variants have been found; COX-1, COX-2 and COX-3. COX-2 is induced by cytokines and mitogens and is thought to play a role in inflammatory diseases such as rheumatoid arthritis.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (NRGVCMSVGFDQYKCDCTRTGFY) corresponding to a region (28-50) from human Cyclooxygenase-2. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

MSDS (File name) :