Rabbit polyclonal antibody to human Cyclooxygenase-1 (35-52): Affinity purified

ZZZZ_Status (Active, Disc) : Discontinued

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin-endoperoxide synthase 1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; PTGS1;COX1;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5µg/mL is recommended for WB. Human COX-1 (long) has a predicted length of 599 residues and MW of 69 kDa. A concentration of 0.5-1.0 µg/mL is recommended for IHC to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

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Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1187

 

Description (Long Description) : 

Cyclooxygenase (COX) is an important enzyme in the conversion of arachidonic acid to Prostaglandin H2, the precursor of the series-2 prostanoids. At least 3 splice variants have been found (COX-1, COX-2 and COX-3). COX-1 is constitutively expressed in most cell types and is induced as part of the inflammatory response by cytokines as well as by growth factors such as EGF and PDGF.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 added as preservative

 

Immunogen (Antigen) :A synthetic peptide corresponding to a region (35-52 aa) from human Cyclooxygenase-1. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

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