Rabbit polyclonal antibody to human Caspase 2 (417-439): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

CASP-2; ICH-1 protease; CASP2; ICH1; NEDD2;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.5-1.0 µg/mL is recommended for WB. Human Caspase 2 (Isoform ICH-1L) has a predicted length of 452 amino acids and a MW of 51 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=513

 

Description (Long Description) : 

Caspase 2 is a member of the cysteine-aspartic acid protease (caspase) family and acts as both a positive and negative regulator of apoptosis. Overexpression of the full length Caspase 2 (Isoform ICH-1L) in some cell types results in apoptosis whereas the overexpression of an alternative Caspase 2 (ICH-1S) splice variant suppresses apoptosis.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (REGYAPGTEFHRCKEMSEYCSTL) corresponding to a region (417-439) from human Caspase 2

 

Kit_Components :

 

MSDS (File name) :