Rabbit polyclonal antibody to human C-X-C Chemokine receptor 4 (18-33): Affinity purified

Antibodies

貨號 Cat. No.
R-1143-100
規格 Size
100 µg
品牌 Brand
Biosensis
Application 應用
IH,Frozen 、 IH(P), Paraffin 、 WB
Reactivity
Human (WB; IHC) 、 Mouse (Predicted) 、 Rat (WB)
Host
Rabbit
Clonality
Polyclonal

Description




ZZZZ_Status (Active, Disc) : Active


 

AA_Supplier Name : Biosensis


 

Alternative_Name (Other Names) :


C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Stromal cell-derived factor 1 receptor; SDF-1 receptor; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; LCR1; FB22; NPYRL; HM89; CD184; CXCR4;


 

Antibody_Isotype
(Antibody only) :


 

Application_Details :


Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Human CXCR4 (isoform 1) has a predicted length of 352 residues and MW of 40 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect the protein in human formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval (Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins) is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.


 

Background_Info :


 

Clone_Name
(AB only, monoclonals) :


 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=615


 

Description (Long Description) : 


The C-X-C Chemokine receptor 4 (CXCR4) is a multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. CXCR4 is a specific receptor for stromal cell-derived factor-1 (SDF-1) and is widely expressed in tissues including peripheral blood leukocytes, spleen, thymus, spinal cord, heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, cerebellum, cerebral cortex and medulla. At least 2 isoforms are produced by alternative splicing.

 

Expiry_Date : 


12 months after purchase (lyophilized)

 

Format (Form) : 


Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (SGDYDSMKEPCFREEN) corresponding to a region (18-33) from human C-X-C Chemokine receptor 4. To enhance the immunological response, this peptide was coupled to carrier protein BSA.


 

Kit_Components :


 

MSDS (File name) :


 



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