Rabbit polyclonal antibody to human C-C Chemokine Receptor type 5 (19-34): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

C-C CKR-5; CC-CKR-5; CCR-5; CCR5; HIV-1 fusion coreceptor; CHEMR13; CD195;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Human CCR5 has a predicted length of 352 residues and MW of 41 kDa. A concentration of 0.5-1 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=514

 

Description (Long Description) : 

C-C Chemokine Receptor type 5 (CCR5) is a G-protein coupled receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES. CCR5 and its ligands may also play important roles in the control of granulocytic lineage proliferation or differentiation as well as pathogenesis of viruses such as HIV.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (PCQKINVKQIAARLLP) corresponding to a region (19-34) from the N-terminus of human C-C Chemokine Receptor type 5. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

Kit_Components :

 

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