Rabbit polyclonal antibody to FAS (87-109): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

FASLG receptor; Apo-1; CD95; Apt1; Tnfrsf6;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Rat FAS has a predicted length of 324 residues and MW of 37 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues as well as formalin/acetone fixed frozen tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=522

 

Description (Long Description) : 

FAS is a single-pass type I membrane protein and a member of the TNF-receptor superfamily. The interaction between this receptor and the FAS ligand (TNFSF6/FASLG) forms a death-inducing signalling complex that includes Fas-associated death domain protein (FADD), caspase 8 and caspase 10. Processing of the caspases in this complex leads to apoptosis.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (YTDRKHYSDKCRRCAFCDEGHGL) corresponding to a region (87-109) from rat FAS. To enhance the immunological response, this peptide was coupled to carrier protein BSA.

 

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