Rabbit polyclonal antibody to Connexin-26 (211-226): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

GJB2; Cx26; Gap junction beta-2 protein;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. The predicted length of rat Connexin-26 is 226 residues and MW of 26 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=473

 

Description (Long Description) : 

A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighbouring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Liquid (0.5mL). 50% glycerol, 0.9mg NaCl and 0.2mg Na2HPO4

 

Immunogen (Antigen) :A synthetic peptide (CYLFIRYCSGKSKRPV) corresponding to the amino acid sequence 211-226 from rat Connexin-26.

 

Kit_Components :

 

MSDS (File name) :