Rabbit polyclonal antibody to Caspase-8 (223-242): Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH; MCH5;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human Caspase-8 (Isoform 1 precursor) has a predicted length of 479 amino acids and MW of 55 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=975

 

Description (Long Description) : 

Caspase-8 is involved in the programmed cell death induced by Fas and various apoptotic stimuli. Many alternatively spliced transcript variants encoding different isoforms have been described. (Ref: Entrez Gene). Recent observations in microglia have implicated caspase 8 as a modulator of microglial activation in absence of cell death.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

 

Immunogen (Antigen) :A synthetic peptide (DKVYQMKSKPRGYCLIINNH) corresponding to a region (223-242 aa) from human Caspase-8.

 

Kit_Components :

 

MSDS (File name) :