Rabbit antibody to CD133/Prominin-1: Affinity purfied
Antibodies
- 貨號 Cat. No.
- R-1824-100
- 規格 Size
- 100 ug
- 品牌 Brand
- Biosensis
- Application 應用
- IH(P), Paraffin embedded 、 WB
- Reactivity
- Human 、 other species not tested yet.
- Host
- Rabbit
- Clonality
- Polyclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Prominin-1, Prominin-like protein 1, PROM1, PROML1, Antigen AC133, MSTP061; CD133;
Antibody_Isotype
(Antibody only) : IgG
Application_Details :
Western Blot (0.1-0.5 ug/mL): tested in MCF-7 whole cell lysate. Immunohistochemistry: paraffin-embedded section (0.5-1.0 ug/mL) with HIER, pH 6.5; tested in human tonsil tissue. Other applications not yet tested. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) :
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1656
Description (Long Description) :
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439). Ref: uniprot.org.
Expiry_Date :
12 months after purchase if unopened.
Format (Form) :
Lyophilized.
Immunogen (Antigen) :E-coli derived human CD133/PROM1 recombinant protein (position: P531-H865) has been used as the immunogen. Human CD133 shares 61% amino acid sequence identity with mouse CD133.
Kit_Components :
MSDS (File name) :
