Rabbit antibody to ATG16 L1: whole serum

Antibodies

貨號 Cat. No.
R-158-100
規格 Size
100 µL
品牌 Brand
Biosensis
Application 應用
ELISA 、 ICC 、 WBD
Reactivity
Human 、 Rat
Host
Rabbit
Clonality
Polyclonal

Description




ZZZZ_Status (Active, Disc) : Active


 

AA_Supplier Name : Biosensis


 

Alternative_Name (Other Names) :


Autophagy-related protein 16-1; APG16-like 1; ATG16L1


 

Antibody_Isotype
(Antibody only) : Mixed


 

Application_Details :


Non-reduced western blot: 1:100; IP: 1-50-1:100 (5-10uL/500uL lysate); ELISA: 1:2000-1:3000 direct detection only, recombinant immunogen.


 

Background_Info :


 

Clone_Name
(AB only, monoclonals) :


 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=230


 

Description (Long Description) : 


ATG16 L1 plays an essential role in autophagy. It is a homooligomer ant interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). APG16 L1 localises to the cytoplasm, in particularly to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. There are 5 named isoforms produced by alternative splicing. Genetic variation within ATG16 L1 are associated with susceptibility to inflammatory bowel disease type 1.

 

Expiry_Date : 


Six months after purchase

 

Format (Form) : 


Lyophilized

 

Immunogen (Antigen) :N-terminal of human ATG16-L1 protein conjugated to Blue Carrier Protein has been used as the immunogen.


 

Kit_Components :


 

MSDS (File name) :


 



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