Pyroptosis/Caspase-1 activity assay kit (Fluorometric)

Pyroptosis, or caspase 1-dependent programmed cell death, is inherently inflammatory, is triggered by various pathological stimuli and is crucial for controlling microbial infections. Caspase-1 is the key mediator to trigger pyroptosis. Cell Biologics’ Pyroptosis/Caspase-1 activity assay kit (Fluoromeric) is designed to measure caspase-1 activity in cell or tissue lysates by a fluorogenic substrate that produces green fluorescence (λem ~505 nm) upon cleavage of the AFC fluorophore by Caspase-1.