Proteins and Peptides
PTHR1 Antibody (LS-B2267)
- 貨號 Cat. No.
- LS-B2267
- 規格 Size
- 50 µg
- 品牌 Brand
- LSBio
Description
| Antibody Catalog ID: | LS-B2267 |
|---|---|
| Antibody Validation: | This antibody replaces catalog number LS-C25980. It has been validated for use in the following assays: IHC-P. |
| Antibody Target: | Parathyroid Hormone Receptor 1 (PTHR1) |
| Synonyms: | PTHR1, parathyroid hormone receptor 1, parathyroid hormone-related peptide receptor, parathyroid hormone/parathyroid hormone-related peptide receptor, pth-related peptide receptor, pth/pthrp receptor, PTH/PTHrP type I receptor, pthr1, PTHrP-R, PTHrP-receptor |
| Family: | GPCR |
| Subfamily: | Parathyroid hormone |
| Host: | PTHR1 antibody was produced in Mouse |
| Antigen Species: | PTHR1 antibody was raised against Human |
| Clonality: | Monoclonal |
| Isotype: | IgG1,k |
| Antigen Type: | Synthetic peptide |
| Immunogen: | PTHR1 antibody was raised against synthetic peptide corresponding to aa146-169 of human PTH/PTHrP Receptor [RRCDRNGSWELVPGHNRTWANYSE]. Species Sequence Homology: Mouse & rat (23/24aa) |
| Antibody Specificity: | Recognizes human PTH/PTHrP receptor, Mr 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor. Species cross-reactivity: mouse and porcine. |
| Predicted Species Reactivity: | Mouse, Porcine |
| Purification: | Protein G Column |
| Presentation: | 0.014 M PBS, pH 7.6, 0.175 M sodium chloride, 0.07% sodium azide, 30% glycerol. |
| Recommended Storage: | Long term: -20°C; Short term: +4°C |
| Antibody Usage Summary: | Immunohistochemistry: LS-B2267 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D2, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2267 was determined to be 5 ug/ml. Detects PTH/PTHrP receptor in human kidney, vascular smooth muscle and ovary sections. Receptor was also detected in porcine oocytes. |
| Antibody Uses: | Immunohistochemistry (IHC), Immunohistochemistry - Paraffin (IHC-P) (5 µg/ml), Western blot (WB) (0.5 - 2 µg/ml) (Optimal dilution to be determined by the researcher) |
| Size: | 50 µg |
| Concentration: | 1 mg/ml |
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