PSMD14 monoclonal
- 貨號 Cat. No.
- AB-P496
- 規格 Size
- 100 µg
- 品牌 Brand
- Boston Biochem
Description
Catalog #: AB-P496
PSMD14 monoclonal
Product Source:
mouse monoclonal
The proteasome is a large, multimeric protease that catalyzes the final step of the ubiquitin-mediated intracellular protein degradation. The 26S proteasome is an ATP-dependent complex of two copies of the 19S regulator that cap each end of the 20S catalytic core. The 20S is arranged as four axially stacked heptameric rings with multi-catalytic centers located within the internal cavity of the ß-subunits. The 19S caps are composed of 16 different subunits ranging in size from 30 kD to 120 kD and contain ubiquitin chain receptors, ATPase activity and deubiquitinating activities. PSMD14 (POH1) is a 19S Zn++-dependent and deubiquitinating enzyme which is insensitive to ubiquitin-aldehyde inhibition.
Product Information
Quantity:
100 μg
Stock:
100 μg in PBS
Host:
Mouse
Immunogen:
PSMD14 (NP_005796, 1 ~ 96 a.a) partial recombinant protein with GST (26kD)
Epitope:
MLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK
Isotype:
IgG1 Kappa (Clone 4A10-E8)
Reactivity:
Human. Other species not tested.
Western Blot Data:
Use & Storage
Use:
Western blotting, ELISA and IF. Investigator should empirically determine optimal working dilutions. Other applications have not yet been tested.
Storage:
Store at -20oC or -80oC. Aliquot to avoid freeze-thaw cycles.