PSMB8 monoclonal

貨號 Cat. No.
AB-P273
規格 Size
100 μg
品牌 Brand
Boston Biochem

Description

PSMB8 monoclonal

Catalog #: AB-P273




PSMB8 monoclonal






Product Source: 

mouse monoclonal



The proteasome is a large, multimeric protease that catalyzes the final step of the ubiquitin-mediated intracellular protein degradation. The 26S proteasome is an ATP-dependent complex of two copies of the 19S regulator that cap each end of the 20S catalytic core. The 20S is arranged as four axially stacked heptameric rings with multi-catalytic centers located within the internal cavity of the ß-subunits. The 19S caps are composed of 16 different subunits ranging in size from 30 kD to 120 kD and contain ubiquitin chain receptors, ATPase activity and deubiquitinating activities. PSMB8 (LMP7) is a 20S core beta subunit and is found in the immunoproteasome form.


Product Information



Quantity: 

100 μg






Stock: 

100 μg in PBS






Host: 

Mouse






Immunogen: 

PSMB8 (NP_004150, 173 ~ 272 a.a) full length recombinant protein






Epitope: 

DKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRR


AIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREAN








Isotype: 

IgG2a Kappa (Clone 1B3).






Reactivity: 

Human. Other species not tested.






Western Blot Data: 





 


Use & Storage



Use: 

Western blotting, ELISA, IHC and IF. Investigator should empirically determine optimal working dilutions. Other applications have not yet been tested.






Storage: 

Store at -20oC or -80oC. Aliquot to avoid freeze-thaw cycles.



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