PSMA7 monoclonal
- 貨號 Cat. No.
- AB-P173
- 規格 Size
- 100 μg
- 品牌 Brand
- Boston Biochem
Description
PSMA7 monoclonal
mouse monoclonal
Product Information
100 μg
Mouse
PSMA7 (NP_002783.1, 1 ~ 248 a.a) full length recombinant protein with GST (26kD).
Human. Other species not tested.
Use & Storage
Western blotting. Suggested working dilution for all applications are between 1:500 and 1:1000. Investigator should empirically determine optimal working dilutions. Other applications have not yet been tested.
Store at -20oC or -80oC. Aliquot to avoid freeze-thaw cycles.
Catalog #: AB-P173
PSMA7 monoclonal
Product Source:
mouse monoclonal
The proteasome is a large, multimeric protease that catalyzes the final step of the ubiquitin-mediated intracellular protein degradation. The 26S proteasome is an ATP-dependent complex of two copies of the 19S regulator that cap each end of the 20S catalytic core. The 20S is arranged as four axially stacked heptameric rings with multi-catalytic centers located within the internal cavity of the ß-subunits. The 19S caps are composed of 16 different subunits ranging in size from 30 kD to 120 kD and contain ubiquitin chain receptors, ATPase activity and deubiquitinating activities. PSMA7 is a 20S alpha subunit which comprises the outer rings of the proteasome. The C-terminus of PSMA7 interacts with hepatitis B virus X (HBX) protein which interferes with proteasome function. PSMA7 is also phosphorylated by ABL and ARG tyrosine kinases which may regulate proteasome function.
Product Information
Quantity:
100 μg
Host:
Mouse
Immunogen:
PSMA7 (NP_002783.1, 1 ~ 248 a.a) full length recombinant protein with GST (26kD).
Isotype:
MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGV
EKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVEC
QSHRLTVEDPVVEYITRYIASLKQRYTQSNGRRPFGSALIVGFDFDG
TPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLT
IKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEK
EENEKKKQKKAS
Reactivity:
Human. Other species not tested.
Western Blot Data:
Use & Storage
Use:
Western blotting. Suggested working dilution for all applications are between 1:500 and 1:1000. Investigator should empirically determine optimal working dilutions. Other applications have not yet been tested.
Storage:
Store at -20oC or -80oC. Aliquot to avoid freeze-thaw cycles.